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Magnoflorine-Loaded Chitosan Collagen Nanocapsules Ameliorate Cognitive Deficit in Scopolamine-Induced Alzheimer’s Disease-like Conditions in a Rat Model by Downregulating IL-1β, IL-6, TNF-α, and Oxidative Stress and Upregulating Brain-Derived Neurotrophic Factor and DCX Expressions

[Image: see text] Dementia or the loss of cognitive functioning is one of the major health issues in elderly people. Alzheimer’s disease (AD) is one of the common forms of dementia. Treatment chiefly involves the use of acetylcholinesterase (AChE) inhibitors in AD. However, oxidative stress has also...

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Detalles Bibliográficos
Autores principales: Bashir, Dar Junaid, Manzoor, Saliha, Sarfaraj, Mohd, Afzal, Shekh Mohammad, Bashir, Masarat, Nidhi, Rastogi, Shweta, Arora, Indu, Samim, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850486/
https://www.ncbi.nlm.nih.gov/pubmed/36687096
http://dx.doi.org/10.1021/acsomega.2c06467