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Insights into the Mechanism of CRISPR/Cas9-Based Genome Editing from Molecular Dynamics Simulations
[Image: see text] The CRISPR/Cas9 system is a popular genome-editing tool with immense therapeutic potential. It is a simple two-component system (Cas9 protein and RNA) that recognizes the DNA sequence on the basis of RNA:DNA complementarity, and the Cas9 protein catalyzes the double-stranded break...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850488/ https://www.ncbi.nlm.nih.gov/pubmed/36687047 http://dx.doi.org/10.1021/acsomega.2c05583 |