Identifying effect modifiers of CAR-T cell therapeutic efficacy: a systematic review and individual patient data meta-analysis protocol

BACKGROUND: Chimeric antigen receptor T cell therapy (CAR-T) represents a promising and exciting new therapy for hematologic malignancies, where prognosis for relapsed/refractory patients remains poor. Encouraging results from clinical trials have often been tempered by heterogeneity in response to...

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Detalles Bibliográficos
Autores principales: Lalu, Manoj M., Kekre, Natasha, Montroy, Joshua, Ghiasi, Maryam, Hay, Kevin, McComb, Scott, Weeratna, Risini, Atkins, Harold, Hutton, Brian, Yahya, Ayel, Masurekar, Ashish, Sobh, Mohamad, Fergusson, Dean A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850506/
https://www.ncbi.nlm.nih.gov/pubmed/36653879
http://dx.doi.org/10.1186/s13643-022-02158-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850506/
https://www.ncbi.nlm.nih.gov/pubmed/36653879
http://dx.doi.org/10.1186/s13643-022-02158-1

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