Sleep fragmentation affects glymphatic system through the different expression of AQP4 in wild type and 5xFAD mouse models

Alzheimer’s disease (AD) is characterized by genetic and multifactorial risk factors. Many studies correlate AD to sleep disorders. In this study, we performed and validated a mouse model of AD and sleep fragmentation, which properly mimics a real condition of intermittent awakening. We noticed that...

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Detalles Bibliográficos
Autores principales: Vasciaveo, Valeria, Iadarola, Antonella, Casile, Antonino, Dante, Davide, Morello, Giulia, Minotta, Lorenzo, Tamagno, Elena, Cicolin, Alessandro, Guglielmotto, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850555/
https://www.ncbi.nlm.nih.gov/pubmed/36653878
http://dx.doi.org/10.1186/s40478-022-01498-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850555/
https://www.ncbi.nlm.nih.gov/pubmed/36653878
http://dx.doi.org/10.1186/s40478-022-01498-2

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