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Impact of aza-substitutions on the preference of helix handedness for β-peptide oligomers: a DFT study
We studied the helix preference of the heterochiral pentamers of cis-2-aminocyclohexanecarboxylic acid (c-ACHC) and cis-2-aminocyclopentanecarboxylic acid (c-ACPC) with alternating backbone configurations by replacing C(β)-aza- or C(α)-aza-peptide residues using DFT methods in solution. The helix-ha...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society of Chemistry
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850699/ https://www.ncbi.nlm.nih.gov/pubmed/36756412 http://dx.doi.org/10.1039/d2ra07575j |