Effects of Chemical Additives in Refolding Buffer on Recombinant Human BMP-2 Dimerization and the Bioactivity on SaOS-2 Osteoblasts

[Image: see text] Bone morphogenetic protein-2 (BMP-2) is a promising osteogenic agent in tissue engineering. BMP-2 is usually expressed in Escherichia coli owing to the high yield and low cost, but the protein is expressed as inclusion bodies. Thus, the bottleneck for BMP-2 production in E. coli is...

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Detalles Bibliográficos
Autores principales: Manissorn, Juthatip, Tonsomboon, Khaow, Wangkanont, Kittikhun, Thongnuek, Peerapat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850730/
https://www.ncbi.nlm.nih.gov/pubmed/36687022
http://dx.doi.org/10.1021/acsomega.2c05802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850730/
https://www.ncbi.nlm.nih.gov/pubmed/36687022
http://dx.doi.org/10.1021/acsomega.2c05802

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