Cargando…
Peptidoglycan-Directed Chemical Ligation for Selective Inhibition on Gram-Positive Bacteria
[Image: see text] Microbicides with distinct antibacterial mechanisms show potential to combat multi-drug resistance bacteria. We herein report peptidoglycan-directed chemical ligation (PGCL) between alkyne-bearing vancomycin and an azide-tagged cationic polymer. The former binds peptidoglycan and i...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850734/ https://www.ncbi.nlm.nih.gov/pubmed/36687063 http://dx.doi.org/10.1021/acsomega.2c06964 |