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Peptidoglycan-Directed Chemical Ligation for Selective Inhibition on Gram-Positive Bacteria

[Image: see text] Microbicides with distinct antibacterial mechanisms show potential to combat multi-drug resistance bacteria. We herein report peptidoglycan-directed chemical ligation (PGCL) between alkyne-bearing vancomycin and an azide-tagged cationic polymer. The former binds peptidoglycan and i...

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Detalles Bibliográficos
Autores principales: Jiang, Feng, Cai, Chengteng, Gao, Lei, Su, Xinhui, Han, Shoufa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850734/
https://www.ncbi.nlm.nih.gov/pubmed/36687063
http://dx.doi.org/10.1021/acsomega.2c06964