Interspecies recombination, not de novo mutation, maintains virulence after β-lactam resistance acquisition in Streptococcus pneumoniae

As opposed to de novo mutation, β-lactam resistance in S. pneumoniae is often conferred via homologous recombination during horizontal gene transfer. We hypothesize that β-lactam resistance in pathogenic streptococci is restricted to naturally competent species via intra-/interspecies recombination...

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Detalles Bibliográficos
Autores principales: Nishimoto, Andrew T., Dao, Tina H., Jia, Qidong, Ortiz-Marquez, Juan C., Echlin, Haley, Vogel, Peter, van Opijnen, Tim, Rosch, Jason W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850807/
https://www.ncbi.nlm.nih.gov/pubmed/36516783
http://dx.doi.org/10.1016/j.celrep.2022.111835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850807/
https://www.ncbi.nlm.nih.gov/pubmed/36516783
http://dx.doi.org/10.1016/j.celrep.2022.111835

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