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Accounting for cis-regulatory constraint prioritizes genes likely to affect species-specific traits

Measuring allele-specific expression in interspecies hybrids is a powerful way to detect cis-regulatory changes underlying adaptation. However, it remains difficult to identify genes most likely to explain species-specific traits. Here, we outline a simple strategy that leverages population-scale al...

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Detalles Bibliográficos
Autores principales: Starr, Alexander L., Gokhman, David, Fraser, Hunter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850818/
https://www.ncbi.nlm.nih.gov/pubmed/36658652
http://dx.doi.org/10.1186/s13059-023-02846-8