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Z-Guggulsterone Induces Cell Cycle Arrest and Apoptosis by Targeting the p53/CCNB1/PLK1 Pathway in Triple-Negative Breast Cancer

[Image: see text] Myrrh is the dried resin of Commiphora Myrrh Engl., which exerts anticancer properties. However, its effects and molecular mechanisms in triple-negative breast cancer (TNBC) remain unclear. In this study, we used network pharmacology to screen Z-Guggulsterone (Z-GS) as a characteri...

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Detalles Bibliográficos
Autores principales: Wu, Yihao, Zhou, Tao, Qian, Da, Liu, Xiaozhen, Xu, Yuhao, Hong, Weimin, Meng, Xuli, Tang, Hongchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851028/
https://www.ncbi.nlm.nih.gov/pubmed/36687039
http://dx.doi.org/10.1021/acsomega.2c07480