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Design, Synthesis, In Vivo, and In Silico Evaluation of Benzothiazoles Bearing a 1,3,4-Oxadiazole Moiety as New Antiepileptic Agents

[Image: see text] In the presented manuscript, a new series of 2-[4-methoxy-3-(5-substituted phenyl-[1,3,4]oxadiazol-2-ylmethoxy)-phenyl]-benzothiazoles (6a–n) have been synthesized and studied in vivo and in silico for their anticonvulsant potential. Maximum electroshocks (MES) and subcutaneous pen...

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Detalles Bibliográficos
Autores principales: Chauhan, Bharti, Kumar, Rajnish, Salahuddin, Singh, Himanshu, Afzal, Obaid, Altamimi, Abdulmalik Saleh Alfawaz, Abdullah, Mohd Mustaqeem, Yar, Mohammad Shahar, Ahsan, Mohamed Jawed, Kumar, Neeraj, Yadav, Sanjay Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851031/
https://www.ncbi.nlm.nih.gov/pubmed/36687046
http://dx.doi.org/10.1021/acsomega.2c06967