Cargando…
Design, Synthesis, In Vivo, and In Silico Evaluation of Benzothiazoles Bearing a 1,3,4-Oxadiazole Moiety as New Antiepileptic Agents
[Image: see text] In the presented manuscript, a new series of 2-[4-methoxy-3-(5-substituted phenyl-[1,3,4]oxadiazol-2-ylmethoxy)-phenyl]-benzothiazoles (6a–n) have been synthesized and studied in vivo and in silico for their anticonvulsant potential. Maximum electroshocks (MES) and subcutaneous pen...
Autores principales: | Chauhan, Bharti, Kumar, Rajnish, Salahuddin, Singh, Himanshu, Afzal, Obaid, Altamimi, Abdulmalik Saleh Alfawaz, Abdullah, Mohd Mustaqeem, Yar, Mohammad Shahar, Ahsan, Mohamed Jawed, Kumar, Neeraj, Yadav, Sanjay Kumar |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851031/ https://www.ncbi.nlm.nih.gov/pubmed/36687046 http://dx.doi.org/10.1021/acsomega.2c06967 |
Ejemplares similares
-
Design, Synthesis,
ADME, and Anticancer Studies of
Newer N-Aryl-5-(3,4,5-Trifluorophenyl)-1,3,4-Oxadiazol-2-Amines:
An Insight into Experimental and Theoretical Investigations
por: Agarwal, Mohit, et al.
Publicado: (2023) -
Synthesis and Anticancer Evaluation of 4-Chloro-2-((5-aryl-1,3,4-oxadiazol-2-yl)amino)phenol Analogues: An Insight into Experimental and Theoretical Studies
por: Afzal, Obaid, et al.
Publicado: (2023) -
Chemical Modification of Curcumin into Its Semi-Synthetic Analogs Bearing Pyrimidinone Moiety as Anticancer Agents
por: Afzal, Obaid, et al.
Publicado: (2022) -
Pyrazoline Containing
Compounds as Therapeutic Targets
for Neurodegenerative Disorders
por: Ahsan, Mohamed Jawed, et al.
Publicado: (2022) -
Synthesis and In Vitro Antimicrobial Evaluation of New 1,3,4-Oxadiazoles Bearing 5-Chloro-2-methoxyphenyl Moiety
por: Prasanna Kumar, Basavapatna N., et al.
Publicado: (2013)