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Transcriptome and single-cell analysis reveal the contribution of immunosuppressive microenvironment for promoting glioblastoma progression

BACKGROUND AND OBJECTIVES: GBM patients frequently exhibit severe local and systemic immunosuppression, limiting the possible efficacy of immunotherapy strategies. The mechanism through which immunosuppression is established in GBM tumors is the key to successful personalized immunotherapies. METHOD...

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Detalles Bibliográficos
Autores principales: Ni, Lulu, Sun, Ping, Zhang, Sujuan, Qian, Bin, Chen, Xu, Xiong, Mengrui, Li, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851159/
https://www.ncbi.nlm.nih.gov/pubmed/36685556
http://dx.doi.org/10.3389/fimmu.2022.1051701