Validation of transcriptome signature reversion for drug repurposing in oncology

Transcriptome signature reversion (TSR) has been extensively proposed and used to discover new indications for existing drugs (i.e. drug repositioning, drug repurposing) for various cancer types. TSR relies on the assumption that a drug that can revert gene expression changes induced by a disease ba...

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Detalles Bibliográficos
Autores principales: Koudijs, Karel K M, Böhringer, Stefan, Guchelaar, Henk-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Problem Solving Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851289/
https://www.ncbi.nlm.nih.gov/pubmed/36445193
http://dx.doi.org/10.1093/bib/bbac490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851289/
https://www.ncbi.nlm.nih.gov/pubmed/36445193
http://dx.doi.org/10.1093/bib/bbac490

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