Discovery of fusion circular RNAs in leukemia with KMT2A::AFF1 rearrangements by the new software CircFusion

Chromosomal translocations in cancer genomes, key players in many types of cancers, generate chimeric proteins that drive oncogenesis. Genomes with chromosomal rearrangements can also produce fusion circular RNAs (f-circRNAs) by backsplicing of chimeric transcripts, as first shown in leukemias with...

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Detalles Bibliográficos
Autores principales: Dal Molin, Anna, Tretti Parenzan, Caterina, Gaffo, Enrico, Borin, Cristina, Boldrin, Elena, Meyer, Lueder H, te Kronnie, Geertruij, Bresolin, Silvia, Bortoluzzi, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Case Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851293/
https://www.ncbi.nlm.nih.gov/pubmed/36585787
http://dx.doi.org/10.1093/bib/bbac589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851293/
https://www.ncbi.nlm.nih.gov/pubmed/36585787
http://dx.doi.org/10.1093/bib/bbac589

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