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Improving therapeutic synergy score predictions with adverse effects using multi-task heterogeneous network learning

Drug combinations could trigger pharmacological therapeutic effects (TEs) and adverse effects (AEs). Many computational methods have been developed to predict TEs, e.g. the therapeutic synergy scores of anti-cancer drug combinations, or AEs from drug–drug interactions. However, most of the methods t...

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Detalles Bibliográficos
Autores principales: Yue, Yang, Liu, Yongxuan, Hao, Luoying, Lei, Huangshu, He, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851313/
https://www.ncbi.nlm.nih.gov/pubmed/36562724
http://dx.doi.org/10.1093/bib/bbac564