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Combination Chemotherapy of Multidrug-resistant Early-stage Colon Cancer: Determining Optimal Dose Schedules by High-performance Computer Simulation
The goal of this project was to utilize mechanistic simulation to demonstrate a methodology that could determine drug combination dose schedules and dose intensities that would be most effective in eliminating multidrug-resistant cancer cells in early-stage colon cancer. An agent-based model of cell...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Association for Cancer Research
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851383/ https://www.ncbi.nlm.nih.gov/pubmed/36685168 http://dx.doi.org/10.1158/2767-9764.CRC-22-0271 |