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YAP–VGLL4 antagonism defines the major physiological function of the Hippo signaling effector YAP

The Hippo–YAP signaling pathway plays a critical role in development, homeostasis, regeneration, and tumorigenesis by converging on YAP, a coactivator for the TEAD family DNA-binding transcription factors, to regulate downstream transcription programs. Given its pivotal role as the nuclear effector...

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Detalles Bibliográficos
Autores principales: Cai, Jing, Choi, Kyungsuk, Li, Hongde, Pulgar Prieto, Katiuska Daniela, Zheng, Yonggang, Pan, Duojia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851404/
https://www.ncbi.nlm.nih.gov/pubmed/36522128
http://dx.doi.org/10.1101/gad.350127.122