Cargando…

ATP—Sensitive Potassium Channel Opener Diazoxide Reduces Myocardial Stunning in a Porcine Regional With Subsequent Global Ischemia Model

BACKGROUND: ATP‐sensitive potassium channels are inhibited by ATP and open during metabolic stress, providing endogenous myocardial protection. Pharmacologic opening of ATP potassium channels with diazoxide preserves myocardial function following prolonged global ischemia, making it an ideal candida...

Descripción completa

Detalles Bibliográficos
Autores principales: Velez, Ana K., Etchill, Eric, Giuliano, Katherine, Kearney, Sean, Jones, Melissa, Wang, Jie, Cho, Brian, Brady, Mary Beth, Dodd‐o, Jeffrey, Meyer, Joseph M., Lawton, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851454/
https://www.ncbi.nlm.nih.gov/pubmed/36444837
http://dx.doi.org/10.1161/JAHA.122.026304