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ATP—Sensitive Potassium Channel Opener Diazoxide Reduces Myocardial Stunning in a Porcine Regional With Subsequent Global Ischemia Model
BACKGROUND: ATP‐sensitive potassium channels are inhibited by ATP and open during metabolic stress, providing endogenous myocardial protection. Pharmacologic opening of ATP potassium channels with diazoxide preserves myocardial function following prolonged global ischemia, making it an ideal candida...
Autores principales: | Velez, Ana K., Etchill, Eric, Giuliano, Katherine, Kearney, Sean, Jones, Melissa, Wang, Jie, Cho, Brian, Brady, Mary Beth, Dodd‐o, Jeffrey, Meyer, Joseph M., Lawton, Jennifer S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851454/ https://www.ncbi.nlm.nih.gov/pubmed/36444837 http://dx.doi.org/10.1161/JAHA.122.026304 |
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