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Interdomain dynamics in human Replication Protein A regulates kinetics and thermodynamics of its binding to ssDNA
Human Replication Protein A (hRPA) is a multidomain protein that interacts with ssDNA intermediates to provide the latter much-needed stability during DNA metabolism and maintain genomic integrity. Although the ssDNA organization with hRPA was studied recently through experimental means, characteriz...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851514/ https://www.ncbi.nlm.nih.gov/pubmed/36656834 http://dx.doi.org/10.1371/journal.pone.0278396 |