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C. elegans XMAP215/ZYG-9 and TACC/TAC-1 act at multiple times during oocyte meiotic spindle assembly and promote both spindle pole coalescence and stability

The conserved two-component XMAP215/TACC modulator of microtubule stability is required in multiple animal phyla for acentrosomal spindle assembly during oocyte meiotic cell division. In C. elegans, XMAP215/zyg-9 and TACC/tac-1 mutant oocytes exhibit multiple and indistinguishable oocyte spindle ass...

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Detalles Bibliográficos
Autores principales: Harvey, Austin M., Chuang, Chien-Hui, Sumiyoshi, Eisuke, Bowerman, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851561/
https://www.ncbi.nlm.nih.gov/pubmed/36608115
http://dx.doi.org/10.1371/journal.pgen.1010363