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Adaptive evolutionary strategy coupled with an optimized biosynthesis process for the efficient production of pyrroloquinoline quinone from methanol

BACKGROUND: Pyrroloquinoline quinone (PQQ), a cofactor for bacterial dehydrogenases, is associated with biological processes such as mitochondriogenesis, reproduction, growth, and aging. Due to the extremely high cost of chemical synthesis and low yield of microbial synthesis, the election of effect...

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Detalles Bibliográficos
Autores principales: Ren, Yang, Yang, Xinwei, Ding, Lingtao, Liu, Dongfang, Tao, Yong, Huang, Jianzhong, Ke, Chongrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851590/
https://www.ncbi.nlm.nih.gov/pubmed/36658601
http://dx.doi.org/10.1186/s13068-023-02261-y