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Single-cell transcriptomic profiling of the zebrafish inner ear reveals molecularly distinct hair cell and supporting cell subtypes

A major cause of human deafness and vestibular dysfunction is permanent loss of the mechanosensory hair cells of the inner ear. In non-mammalian vertebrates such as zebrafish, regeneration of missing hair cells can occur throughout life. While a comparative approach has the potential to reveal the b...

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Detalles Bibliográficos
Autores principales: Shi, Tuo, Beaulieu, Marielle O, Saunders, Lauren M, Fabian, Peter, Trapnell, Cole, Segil, Neil, Crump, J Gage, Raible, David W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851615/
https://www.ncbi.nlm.nih.gov/pubmed/36598134
http://dx.doi.org/10.7554/eLife.82978