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Mechanosensitive miR-99b mediates the regulatory effect of matrix stiffness on bone marrow mesenchymal stem cell fate both in vitro and in vivo

Mechanical signals from extracellular matrix stiffness are important cues that regulate the proliferation and differentiation of bone marrow mesenchymal stem cells (BMSCs). However, the incorporation of BMSCs into soft hydrogels and the dominance of soft matrices for BMSC growth and differentiation...

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Detalles Bibliográficos
Autores principales: Cao, Bojun, Li, Jiaxin, Wang, Xiaowen, Ran, Zhaoyang, Tan, Jia, Deng, Liang, Hao, Yongqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851713/
https://www.ncbi.nlm.nih.gov/pubmed/36685676
http://dx.doi.org/10.1063/5.0131125