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SARS-CoV-2–encoded ORF8 protein possesses complement inhibitory properties

Hyperactivation of the complement system, a major component of innate immunity, has been recognized as one of the core clinical features in severe covid-19 patients. However, how the virus escapes the targeted elimination by the network of activated complement pathways still remains an enigma. Here,...

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Detalles Bibliográficos
Autores principales: Kumar, Jitendra, Dhyani, Saurabh, Kumar, Prateek, Sharma, Nishi Raj, Ganguly, Surajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851726/
https://www.ncbi.nlm.nih.gov/pubmed/36682494
http://dx.doi.org/10.1016/j.jbc.2023.102930