Cargando…
SARS-CoV-2–encoded ORF8 protein possesses complement inhibitory properties
Hyperactivation of the complement system, a major component of innate immunity, has been recognized as one of the core clinical features in severe covid-19 patients. However, how the virus escapes the targeted elimination by the network of activated complement pathways still remains an enigma. Here,...
Autores principales: | Kumar, Jitendra, Dhyani, Saurabh, Kumar, Prateek, Sharma, Nishi Raj, Ganguly, Surajit |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851726/ https://www.ncbi.nlm.nih.gov/pubmed/36682494 http://dx.doi.org/10.1016/j.jbc.2023.102930 |
Ejemplares similares
-
TMEM2 is a bona fide hyaluronidase possessing intrinsic catalytic activity
por: Narita, Takuma, et al.
Publicado: (2023) -
The complement cascade in the regulation of neuroinflammation, nociceptive sensitization, and pain
por: Warwick, Charles A., et al.
Publicado: (2021) -
Identification of an inhibitory domain in GTPase-activating protein p190RhoGAP responsible for masking its functional GAP domain
por: Héraud, Capucine, et al.
Publicado: (2022) -
Protection of eIF2B from inhibitory phosphorylated eIF2: A viral strategy to maintain mRNA translation during the PKR-triggered integrated stress response
por: Ito, Takuhiro, et al.
Publicado: (2023) -
Role of host factors in SARS-CoV-2 entry
por: Evans, John P., et al.
Publicado: (2021)