Diverse silent chromatin states modulate genome compartmentalization and loop extrusion barriers

The relationships between chromosomal compartmentalization, chromatin state and function are poorly understood. Here by profiling long-range contact frequencies in HCT116 colon cancer cells, we distinguish three silent chromatin states, comprising two types of heterochromatin and a state enriched fo...

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Detalles Bibliográficos
Autores principales: Spracklin, George, Abdennur, Nezar, Imakaev, Maxim, Chowdhury, Neil, Pradhan, Sriharsa, Mirny, Leonid A., Dekker, Job
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851908/
https://www.ncbi.nlm.nih.gov/pubmed/36550219
http://dx.doi.org/10.1038/s41594-022-00892-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851908/
https://www.ncbi.nlm.nih.gov/pubmed/36550219
http://dx.doi.org/10.1038/s41594-022-00892-7

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