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Development of highly effective LCB1-based lipopeptides targeting the spike receptor-binding motif of SARS-CoV-2
LCB1 is a computationally designed 56-mer miniprotein targeting the spike (S) receptor-binding motif of SARS-CoV- 2 with high potent activity (Science, 2020; Cell host microbe, 2021); however, recent studies have demonstrated that emerging SARS-CoV-2 variants are highly resistant to LCB1's inhi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier B.V.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851916/ https://www.ncbi.nlm.nih.gov/pubmed/36682464 http://dx.doi.org/10.1016/j.antiviral.2023.105541 |