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Development of highly effective LCB1-based lipopeptides targeting the spike receptor-binding motif of SARS-CoV-2

LCB1 is a computationally designed 56-mer miniprotein targeting the spike (S) receptor-binding motif of SARS-CoV- 2 with high potent activity (Science, 2020; Cell host microbe, 2021); however, recent studies have demonstrated that emerging SARS-CoV-2 variants are highly resistant to LCB1's inhi...

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Detalles Bibliográficos
Autores principales:	Zhu, Yuanmei, Li, Min, Liu, Nian, Wu, Tong, Han, Xuelian, Zhao, Guangyu, He, Yuxian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Authors. Published by Elsevier B.V. 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851916/ https://www.ncbi.nlm.nih.gov/pubmed/36682464 http://dx.doi.org/10.1016/j.antiviral.2023.105541

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