Uncovering the mechanism for aggregation in repeat expanded RNA reveals a reentrant transition

RNA molecules aggregate under certain conditions. The resulting condensates are implicated in human neurological disorders, and can potentially be designed towards specified bulk properties in vitro. However, the mechanism for aggregation—including how aggregation properties change with sequence and...

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Detalles Bibliográficos
Autores principales: Kimchi, Ofer, King, Ella M., Brenner, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852226/
https://www.ncbi.nlm.nih.gov/pubmed/36658112
http://dx.doi.org/10.1038/s41467-023-35803-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852226/
https://www.ncbi.nlm.nih.gov/pubmed/36658112
http://dx.doi.org/10.1038/s41467-023-35803-x

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