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Uncovering the mechanism for aggregation in repeat expanded RNA reveals a reentrant transition
RNA molecules aggregate under certain conditions. The resulting condensates are implicated in human neurological disorders, and can potentially be designed towards specified bulk properties in vitro. However, the mechanism for aggregation—including how aggregation properties change with sequence and...
Autores principales: | Kimchi, Ofer, King, Ella M., Brenner, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852226/ https://www.ncbi.nlm.nih.gov/pubmed/36658112 http://dx.doi.org/10.1038/s41467-023-35803-x |
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