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Optimized immunosuppression to prevent graft failure in renal transplant recipients with HLA antibodies (OuTSMART): a randomised controlled trial

BACKGROUND: 3% of kidney transplant recipients return to dialysis annually upon allograft failure. Development of antibodies (Ab) against human leukocyte antigens (HLA) is a validated prognostic biomarker of allograft failure. We tested whether screening for HLA Ab, combined with an intervention to...

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Detalles Bibliográficos
Autores principales: Stringer, Dominic, Gardner, Leanne, Shaw, Olivia, Clarke, Brendan, Briggs, David, Worthington, Judith, Buckland, Matthew, Danzi, Guilherme, Hilton, Rachel, Picton, Michael, Thuraisingham, Raj, Borrows, Richard, Baker, Richard, McCullough, Keith, Stoves, John, Phanish, Mysore, Shah, Sapna, Shiu, Kin Yee, Walsh, Stephen B., Ahmed, Aimun, Ayub, Waqar, Hegarty, Janet, Tinch-Taylor, Rose, Georgiou, Evangelos, Bidad, Natalie, Kılıç, Ayşenur, Moon, Zoe, Horne, Robert, McCrone, Paul, Kelly, Joanna, Murphy, Caroline, Peacock, Janet, Dorling, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852275/
https://www.ncbi.nlm.nih.gov/pubmed/36684392
http://dx.doi.org/10.1016/j.eclinm.2022.101819