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Characterization of cell-to-cell variation in nuclear transport rates and identification of its sources
Nuclear transport is an essential part of eukaryotic cell function. Here, we present scFRAP, a model-assisted fluorescent recovery after photobleaching (FRAP)- based method to determine nuclear import and export rates independently in individual live cells. To overcome the inherent noise of single-c...
Autores principales: | Durrieu, Lucía, Bush, Alan, Grande, Alicia, Johansson, Rikard, Janzén, David, Katz, Andrea, Cedersund, Gunnar, Colman-Lerner, Alejandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852351/ https://www.ncbi.nlm.nih.gov/pubmed/36686393 http://dx.doi.org/10.1016/j.isci.2022.105906 |
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