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Brain proteome‐wide association study linking‐genes in multiple sclerosis pathogenesis
OBJECTIVES: To identify genes that confer MS risk via the alteration of cis‐regulated protein abundance and verify their aberrant expression in human brain. METHODS: Utilizing a two‐stage proteome‐wide association study (PWAS) design, MS GWAS data (N = 41,505) was respectively integrated with two di...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852387/ https://www.ncbi.nlm.nih.gov/pubmed/36475386 http://dx.doi.org/10.1002/acn3.51699 |