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Brain proteome‐wide association study linking‐genes in multiple sclerosis pathogenesis

OBJECTIVES: To identify genes that confer MS risk via the alteration of cis‐regulated protein abundance and verify their aberrant expression in human brain. METHODS: Utilizing a two‐stage proteome‐wide association study (PWAS) design, MS GWAS data (N = 41,505) was respectively integrated with two di...

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Detalles Bibliográficos
Autores principales: Jia, Tingting, Ma, Yanni, Qin, Fengqin, Han, Feng, Zhang, Chengcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852387/
https://www.ncbi.nlm.nih.gov/pubmed/36475386
http://dx.doi.org/10.1002/acn3.51699