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Plasma phosphorylated tau181 predicts cognitive and functional decline

OBJECTIVE: To determine if plasma tau phosphorylated at threonine 181 (p‐tau181) distinguishes pathology‐confirmed Alzheimer's disease (AD) from normal cognition (NC) adults, to test if p‐tau181 predicts cognitive and functional decline, and to validate findings in an external cohort. METHODS:...

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Detalles Bibliográficos
Autores principales: Tropea, Thomas F., Waligorska, Teresa, Xie, Sharon X., Nasrallah, Ilya M., Cousins, Katheryn A. Q., Trojanowski, John Q., Grossman, Murray, Irwin, David J., Weintraub, Daniel, Lee, Edward B., Wolk, David A., Chen‐Plotkin, Alice S., Shaw, Leslie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852389/
https://www.ncbi.nlm.nih.gov/pubmed/36518085
http://dx.doi.org/10.1002/acn3.51695