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Plasma phosphorylated tau181 predicts cognitive and functional decline
OBJECTIVE: To determine if plasma tau phosphorylated at threonine 181 (p‐tau181) distinguishes pathology‐confirmed Alzheimer's disease (AD) from normal cognition (NC) adults, to test if p‐tau181 predicts cognitive and functional decline, and to validate findings in an external cohort. METHODS:...
Autores principales: | Tropea, Thomas F., Waligorska, Teresa, Xie, Sharon X., Nasrallah, Ilya M., Cousins, Katheryn A. Q., Trojanowski, John Q., Grossman, Murray, Irwin, David J., Weintraub, Daniel, Lee, Edward B., Wolk, David A., Chen‐Plotkin, Alice S., Shaw, Leslie M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852389/ https://www.ncbi.nlm.nih.gov/pubmed/36518085 http://dx.doi.org/10.1002/acn3.51695 |
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