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3D osteogenic differentiation of human iPSCs reveals the role of TGFβ signal in the transition from progenitors to osteoblasts and osteoblasts to osteocytes

Although the formation of bone-like nodules is regarded as the differentiation process from stem cells to osteogenic cells, including osteoblasts and osteocytes, the precise biological events during nodule formation are unknown. Here we performed the osteogenic induction of human induced pluripotent...

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Detalles Bibliográficos
Autores principales: Kawai, Shunsuke, Sunaga, Junko, Nagata, Sanae, Nishio, Megumi, Fukuda, Masayuki, Kamakura, Takeshi, Sun, Liping, Jin, Yonghui, Sakamoto, Satoko, Watanabe, Akira, Matsuda, Shuichi, Adachi, Taiji, Toguchida, Junya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852429/
https://www.ncbi.nlm.nih.gov/pubmed/36658197
http://dx.doi.org/10.1038/s41598-023-27556-w