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Phosphosite Scanning reveals a complex phosphorylation code underlying CDK-dependent activation of Hcm1

Ordered cell cycle progression is coordinated by cyclin dependent kinases (CDKs). CDKs often phosphorylate substrates at multiple sites clustered within disordered regions. However, for most substrates, it is not known which phosphosites are functionally important. We developed a high-throughput app...

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Detalles Bibliográficos
Autores principales: Conti, Michelle M., Li, Rui, Narváez Ramos, Michelle A., Zhu, Lihua Julie, Fazzio, Thomas G., Benanti, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852432/
https://www.ncbi.nlm.nih.gov/pubmed/36658165
http://dx.doi.org/10.1038/s41467-023-36035-9