Cargando…
Phosphosite Scanning reveals a complex phosphorylation code underlying CDK-dependent activation of Hcm1
Ordered cell cycle progression is coordinated by cyclin dependent kinases (CDKs). CDKs often phosphorylate substrates at multiple sites clustered within disordered regions. However, for most substrates, it is not known which phosphosites are functionally important. We developed a high-throughput app...
Autores principales: | Conti, Michelle M., Li, Rui, Narváez Ramos, Michelle A., Zhu, Lihua Julie, Fazzio, Thomas G., Benanti, Jennifer A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852432/ https://www.ncbi.nlm.nih.gov/pubmed/36658165 http://dx.doi.org/10.1038/s41467-023-36035-9 |
Ejemplares similares
-
Hcm1 integrates signals from Cdk1 and calcineurin to control cell proliferation
por: Arsenault, Heather E., et al.
Publicado: (2015) -
Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules
por: Zhao, Yingze, et al.
Publicado: (2022) -
PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites
por: Gnad, Florian, et al.
Publicado: (2007) -
Agonist-induced phosphorylation bar code and differential post-activation signaling of the delta opioid receptor revealed by phosphosite-specific antibodies
por: Mann, Anika, et al.
Publicado: (2020) -
Multisite phosphorylation code of CDK
por: Örd, Mihkel, et al.
Publicado: (2019)