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Structural insights into DNA N(6)-adenine methylation by the MTA1 complex

N(6)-methyldeoxyadenine (6mA) has recently been reported as a prevalent DNA modification in eukaryotes. The Tetrahymena thermophila MTA1 complex consisting of four subunits, namely MTA1, MTA9, p1, and p2, is the first identified eukaryotic 6mA methyltransferase (MTase) complex. Unlike the prokaryoti...

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Detalles Bibliográficos
Autores principales: Yan, Junjun, Liu, Feiqing, Guan, Zeyuan, Yan, Xuhui, Jin, Xiaohuan, Wang, Qiang, Wang, Zican, Yan, Junjie, Zhang, Delin, Liu, Zhu, Wu, Shan, Yin, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852454/
https://www.ncbi.nlm.nih.gov/pubmed/36658132
http://dx.doi.org/10.1038/s41421-022-00516-w