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Chemo-drugs in cell microparticles reset antitumor activity of macrophages by activating lysosomal P450 and nuclear hnRNPA2B1

Macrophages in tumors (tumor-associated macrophages, TAMs), a major population within most tumors, play key homeostatic functions by stimulating angiogenesis, enhancing tumor cell growth, and suppressing antitumor immunity. Resetting TAMs by simple, efficacious and safe approach(s) is highly desirab...

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Detalles Bibliográficos
Autores principales: Wei, Keke, Zhang, Huafeng, Yang, Shuaishuai, Cui, Yuxiao, Zhang, Bingxia, Liu, Jincheng, Tang, Liang, Tan, Yaoyao, Liu, Simin, Chen, Shiqi, Yuan, Wu, Luo, Xiao, Chen, Chen, Li, Fei, Liu, Junwei, Chen, Jie, Xu, Pingwei, Lv, Jiadi, Tang, Ke, Zhang, Yi, Ma, Jingwei, Huang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852455/
https://www.ncbi.nlm.nih.gov/pubmed/36658134
http://dx.doi.org/10.1038/s41392-022-01212-7