Cytotoxic CD8(+) T cells target citrullinated antigens in rheumatoid arthritis

The immune mechanisms that mediate synovitis and joint destruction in rheumatoid arthritis (RA) remain poorly defined. Although increased levels of CD8(+) T cells have been described in RA, their function in pathogenesis remains unclear. Here we perform single cell transcriptome and T cell receptor...

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Detalles Bibliográficos
Autores principales: Moon, Jae-Seung, Younis, Shady, Ramadoss, Nitya S., Iyer, Radhika, Sheth, Khushboo, Sharpe, Orr, Rao, Navin L., Becart, Stephane, Carman, Julie A., James, Eddie A., Buckner, Jane H., Deane, Kevin D., Holers, V. Michael, Goodman, Susan M., Donlin, Laura T., Davis, Mark M., Robinson, William H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852471/
https://www.ncbi.nlm.nih.gov/pubmed/36658110
http://dx.doi.org/10.1038/s41467-022-35264-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852471/
https://www.ncbi.nlm.nih.gov/pubmed/36658110
http://dx.doi.org/10.1038/s41467-022-35264-8

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