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Properties of non-coding mutation hotspots as urinary biomarkers for bladder cancer detection

Mutations at specific hotspots in non-coding regions of ADGRG6, PLEKHS1, WDR74, TBC1D12 and LEPROTL1 frequently occur in bladder cancer (BC). These mutations could function as biomarkers for the non-invasive detection of BC but this remains largely unexplored. Massively-parallel sequencing of non-co...

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Detalles Bibliográficos
Autores principales: Baxter, L., Gordon, N. S., Ott, S., Wang, J., Patel, P., Goel, A., Piechocki, K., Silcock, L., Sale, C., Zeegers, M. P., Cheng, K. K., James, N. D., Bryan, R. T., Ward, D. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852567/
https://www.ncbi.nlm.nih.gov/pubmed/36658180
http://dx.doi.org/10.1038/s41598-023-27675-4