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Salivary Huntingtin protein is uniquely associated with clinical features of Huntington’s disease

Measuring Huntingtin (HTT) protein in peripheral cells represents an essential step in biomarker discovery for Huntington’s Disease (HD), however to date, investigations into the salivary expression of HTT has been lacking. In the current study, we quantified total HTT (tHTT) and mutant HTT (mHTT) p...

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Detalles Bibliográficos
Autores principales: Parkin, Georgia M., Corey-Bloom, Jody, Snell, Chase, Smith, Haileigh, Laurenza, Angela, Daldin, Manuel, Bresciani, Alberto, Thomas, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852574/
https://www.ncbi.nlm.nih.gov/pubmed/36658243
http://dx.doi.org/10.1038/s41598-023-28019-y