Large scale phenotype imputation and in vivo functional validation implicate ADAMTS14 as an adiposity gene

Obesity remains an unmet global health burden. Detrimental anatomical distribution of body fat is a major driver of obesity-mediated mortality risk and is demonstrably heritable. However, our understanding of the full genetic contribution to human adiposity is incomplete, as few studies measure adip...

Descripción completa

Detalles Bibliográficos
Autores principales: Kentistou, Katherine A., Luan, Jian’an, Wittemans, Laura B. L., Hambly, Catherine, Klaric, Lucija, Kutalik, Zoltán, Speakman, John R., Wareham, Nicholas J., Kendall, Timothy J., Langenberg, Claudia, Wilson, James F., Joshi, Peter K., Morton, Nicholas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852585/
https://www.ncbi.nlm.nih.gov/pubmed/36658113
http://dx.doi.org/10.1038/s41467-022-35563-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852585/
https://www.ncbi.nlm.nih.gov/pubmed/36658113
http://dx.doi.org/10.1038/s41467-022-35563-0

Ejemplares similares