Genetic Mimicry Analysis Reveals the Specific Lipases Targeted by the ANGPTL3-ANGPTL8 Complex and ANGPTL4

Angiopoietin-like proteins, ANGPTL3, ANGPTL4, and ANGPTL8, are involved in regulating plasma lipids. In vitro and animal-based studies point to LPL and endothelial lipase (EL, LIPG) as key targets of ANGPTLs. To examine the ANGPTL mechanisms for plasma lipid modulation in humans, we pursued a geneti...

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Detalles Bibliográficos
Autores principales: Landfors, Fredrik, Chorell, Elin, Kersten, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852701/
https://www.ncbi.nlm.nih.gov/pubmed/36372100
http://dx.doi.org/10.1016/j.jlr.2022.100313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852701/
https://www.ncbi.nlm.nih.gov/pubmed/36372100
http://dx.doi.org/10.1016/j.jlr.2022.100313

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