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Meningitis-associated pneumococcal serotype 8, ST 53, strain is hypervirulent in a rat model and has non-haemolytic pneumolysin which can be attenuated by liposomes

INTRODUCTION: Streptococcus pneumoniae bacteria cause life-threatening invasive pneumococcal disease (IPD), including meningitis. Pneumococci are classified into serotypes, determined by differences in capsular polysaccharide and both serotype and pneumolysin toxin are associated with disease severi...

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Detalles Bibliográficos
Autores principales: Müller, Annelies, Lekhuleni, Cebile, Hupp, Sabrina, du Plessis, Mignon, Holivololona, Lalaina, Babiychuk, Eduard, Leib, Stephen L., Grandgirard, Denis, Iliev, Asparouh I., von Gottberg, Anne, Hathaway, Lucy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852819/
https://www.ncbi.nlm.nih.gov/pubmed/36683678
http://dx.doi.org/10.3389/fcimb.2022.1106063