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Meningitis-associated pneumococcal serotype 8, ST 53, strain is hypervirulent in a rat model and has non-haemolytic pneumolysin which can be attenuated by liposomes
INTRODUCTION: Streptococcus pneumoniae bacteria cause life-threatening invasive pneumococcal disease (IPD), including meningitis. Pneumococci are classified into serotypes, determined by differences in capsular polysaccharide and both serotype and pneumolysin toxin are associated with disease severi...
Autores principales: | Müller, Annelies, Lekhuleni, Cebile, Hupp, Sabrina, du Plessis, Mignon, Holivololona, Lalaina, Babiychuk, Eduard, Leib, Stephen L., Grandgirard, Denis, Iliev, Asparouh I., von Gottberg, Anne, Hathaway, Lucy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852819/ https://www.ncbi.nlm.nih.gov/pubmed/36683678 http://dx.doi.org/10.3389/fcimb.2022.1106063 |
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