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The mutation in splicing factor genes correlates with unfavorable prognosis, genomic instability, anti-tumor immunosuppression and increased immunotherapy response in pan-cancer

Splicing abnormality resulting from somatic mutations in key splicing factor genes (SFG) has been detected in various cancers. Hence, an in-depth study of splicing factor genes mutations’ impact on pan-cancer is meaningful. This study investigated associations of splicing factor genes mutations with...

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Detalles Bibliográficos
Autores principales: Luo, Jiangti, Chen, Canping, Liu, Zhixian, Wang, Xiaosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9852835/
https://www.ncbi.nlm.nih.gov/pubmed/36684432
http://dx.doi.org/10.3389/fcell.2022.1045130